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Targeting ligands may include monoclonal antibodies (e.g., trastuzumab targeting HER2), peptides (e.g., RGD motifs for integrins), aptamers, or small molecules such as folic acid [113,114,115,116]

Combined sub-threshold doses of 2.5 ng/ml + 10 "13 M Dihexa and 2.5 ng/ml + 10 "13 M Nlel-AnglV phenocopied the effects of each agonist at its biologically active dose alone (mean S.E.M

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